Fast high-resolution metabolite mapping on a preclinical 14.1T scanner using 1H-FID-MRSI
Simicic, Dunja; Alves, Brayan; Mosso, Jessie Julie; Lê, Thanh Phong Kevin; Van Heeswijk, Ruud B.; Starcukova, Jana; Klauser, Antoine; Strasse, Bernhard; Bogner, Wolfgang; Cudalbu, Cristina
2022
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Résumé

1H-MRSI enables a simultaneous acquisition of MR-spectra from multiple spatial locations inside the brain. While 1H-MRSI is increasingly used in the human brain, its implementation in preclinical setting is limited because of the smaller size of rodent brain. At UHF for humans, 1H-FID-MRSI acquisitions are increasingly used (T2 and J-evolution minimization, increased SNR). We present the first implementation of fast 1H-FID-MRSI in the rat brain at 14.1T and exploit its potential for an increased brain coverage, reliable and accurate quantification results and metabolic maps. Our results set the grounds for a wider application of 1H-FID-MRSI in the preclinical setting.

Détails

Titre Fast high-resolution metabolite mapping on a preclinical 14.1T scanner using 1H-FID-MRSI
Auteur(s)/ trice(s) Simicic, Dunja (CIBM Center for Biomedical Imaging, Lausanne, Switzerland ; Animal Imaging and Technology, EPFL, Lausanne, Switzerland ; Laboratory of Functional and Metabolic Imaging, EPFL, Lausanne, Switzerland)
Alves, Brayan (CIBM Center for Biomedical Imaging, Lausanne, Switzerland ; Animal Imaging and Technology, EPFL, Lausanne, Switzerland)
Mosso, Jessie Julie (CIBM Center for Biomedical Imaging, Lausanne, Switzerland ; Animal Imaging and Technology, EPFL, Lausanne, Switzerland ; Laboratory of Functional and Metabolic Imaging, EPFL, Lausanne, Switzerland)
Lê, Thanh Phong Kevin (Geneva School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland ; Laboratory of Functional and Metabolic Imaging, EPFL, Lausanne, Switzerland)
Van Heeswijk, Ruud B. (Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland)
Starcukova, Jana (Institute of Scientific Instruments, Czech Academy of Sciences, Brno, Czech Republic)
Klauser, Antoine (CIBM Center for Biomedical Imaging, Lausanne, Switzerland ; Department of radiology and medical informatics, University of Geneva, Geneva, Switzerland)
Strasse, Bernhard (Department of Radiology, Medical University Vienna, MR Center of Excellence, Vienna, Austria)
Bogner, Wolfgang (Department of Radiology, Medical University Vienna, MR Center of Excellence, Vienna, Austria)
Cudalbu, Cristina (CIBM Center for Biomedical Imaging, Lausanne, Switzerland ; Animal Imaging and Technology, EPFL, Lausanne, Switzerland)
Date 2022-05
Publié dans Proceedings of the joint annual meeting ISMRM-ESMRMB 2022
Pagination 2 p.
Présenté à International Society for Magnetic Resonance in Medicine - European Society for Magnetic Resonance in Medicine and Biology, Londres, 2022-05-07, 2022-05-12
Type de papier short paper
Domaine Santé
Ecole HEdS - Genève
Institut Institut de Recherche de la Haute école de santé de Genève IR-HEdS
Le document apparaît dans Documents de conférences
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