Cervical cancer is an important healthcare problem in sub-Saharan Africa and emphasis should be placed on implementing and strengthening capacities for screening and treating precancerous lesions. The World Health Organization’s recommendation for low- and medium-income countries to accelerate cervical cancer elimination is human papillomavirus-based primary screening followed directly by treatment or by triage with visual inspection with acetic acid then followed by treatment. To promote these approaches in a community health-care facility, a structurally and functionally dedicated cervical cancer screening and treatment clinic is required. Publications with practical details are rare in literature, imposing a challenge in such planning. In order to provide a toolkit and guidance for health professionals who plan to set up such a clinic, we herein report our experiences in the implementation and running of a cervical cancer screening and treatment clinic adapted to a district level.