Functional electrical stimulation : a new therapeutic approach to enhance exercise intensity in chronic obstructive pulmonary disease patients : a randomized, controlled crossover trial

Medrinal, Clément (Normandy University, UNIROUEN, and the Institute for Research and Innovation in Biomedicine, Rouen, France ; Pulmonology Department, Le Havre Hospital, Montivilliers, France) ; Prieur, Guillaume (Pulmonology Department, Le Havre Hospital, Montivilliers, France) ; Combret, Yann (Institute for Experimental Research, Pulmonology, ORL & Dermatology, Catholic University of Louvain, Brussels, Belgium ; Physiotherapy Department, Le Havre Hospital, Montivilliers, France) ; Robledo Quesada, Aurora (Intensive Care Unit Department, Le Havre Hospital, Montivilliers, France) ; Debeaumont, David (Exercise and Respiratory Physiology Department, Bois Guillaume Hospital, Rouen University Hospital, Rouen Cedex, France) ; Bonnevie, Tristan (Normandy University, UNIROUEN, and the Institute for Research and Innovation in Biomedicine, Rouen, France ; ADIR Association, Bois Guillaume, France) ; Gravier, Francis Edouard (Normandy University, UNIROUEN, and the Institute for Research and Innovation in Biomedicine, Rouen, France ; ADIR Association, Bois Guillaume, France) ; Dupuis Lozeron, Elise (Division of Clinical Epidemiology, Geneva University Hospitals, Geneva, Switzerland) ; Quieffin, Jean (Pulmonology Department, Le Havre Hospital, Montivilliers, France) ; Contal, Olivier (HESAV School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland) ; Lamia, Bouchra (Normandy University, UNIROUEN, and the Institute for Research and Innovation in Biomedicine, Rouen, France ; Pulmonology Department, Le Havre Hospital, Montivilliers, France : Intensive Care Unit, Respiratory Department, Rouen University Hospital, Rouen, France)

Objective To evaluate the effect of quadriceps functional electrical stimulation (FES)-cycling on exertional oxygen uptake (Math Eqo2) compared with placebo FES-cycling in patients with chronic obstructive pulmonary disease (COPD). Design A randomized, single-blind, placebo-controlled crossover trial. Setting Pulmonary rehabilitation department. Participants Consecutive patients (N=23) with COPD Global Initiative for Chronic Obstructive Lung Disease stage 2, 3, or 4 (mean forced expiratory volume during the first second, 1.4±0.4L [50.3% predicted]) who had recently begun a respiratory rehabilitation program. Intervention Two consecutive 30-minute sessions were carried out at a constant load with active and placebo FES-cycling. Main Outcome Measures The primary outcome was mean Math Eqo2 during the 30-minute exercise session. The secondary outcomes were respiratory gas exchange and hemodynamic parameters averaged over the 30-minute endurance session. Lactate values, dyspnea, and perceived muscle fatigue were evaluated at the end of the sessions. Results FES-cycling increased the physiological response more than the placebo, with a greater Math Eqo2 achieved of 36.6mL/min (95% confidence interval [CI], 8.9–64.3mL/min) (P=.01). There was also a greater increase in lactate after FES-cycling (+1.5mmol/L [95% CI, .05–2.9mmol/L]; P=.01). FES-cycling did not change dyspnea or muscle fatigue compared with the placebo condition. Conclusions FES-cycling effectively increased exercise intensity in patients with COPD. Further studies should evaluate longer-term FES-cycling rehabilitation programs.


Keywords:
Article Type:
scientifique
Faculty:
Santé
Branch:
Physiothérapie
School:
HESAV
Institute:
Unité de recherche en santé, HESAV
Subject(s):
Santé
Date:
2018-08
Pagination:
8 p.
Published in:
Archives of physical medicine and rehabilitation
Numeration (vol. no.):
2018, vol. 99, no. 8, pp. 1454-1461
DOI:
ISSN:
0003-9993
External resources:
Appears in Collection:

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 Record created 2019-02-18, last modified 2019-02-22

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