000003192 001__ 3192
000003192 005__ 20190222205057.0
000003192 022__ $$a0003-9993
000003192 0247_ $$2DOI$$a10.1016/j.apmr.2018.02.002
000003192 037__ $$aARTICLE
000003192 041__ $$aeng
000003192 245__ $$aFunctional electrical stimulation :$$ba new therapeutic approach to enhance exercise intensity in chronic obstructive pulmonary disease patients : a randomized, controlled crossover trial
000003192 260__ $$c2018-08
000003192 269__ $$a2018-08
000003192 300__ $$a8 p.
000003192 506__ $$avisible
000003192 520__ $$9eng$$aObjective
To evaluate the effect of quadriceps functional electrical stimulation (FES)-cycling on exertional oxygen uptake (Math Eqo2) compared with placebo FES-cycling in patients with chronic obstructive pulmonary disease (COPD).
Design
A randomized, single-blind, placebo-controlled crossover trial.
Setting
Pulmonary rehabilitation department.
Participants
Consecutive patients (N=23) with COPD Global Initiative for Chronic Obstructive Lung Disease stage 2, 3, or 4 (mean forced expiratory volume during the first second, 1.4±0.4L [50.3% predicted]) who had recently begun a respiratory rehabilitation program.
Intervention
Two consecutive 30-minute sessions were carried out at a constant load with active and placebo FES-cycling.
Main Outcome Measures
The primary outcome was mean Math Eqo2 during the 30-minute exercise session. The secondary outcomes were respiratory gas exchange and hemodynamic parameters averaged over the 30-minute endurance session. Lactate values, dyspnea, and perceived muscle fatigue were evaluated at the end of the sessions.
Results
FES-cycling increased the physiological response more than the placebo, with a greater Math Eqo2 achieved of 36.6mL/min (95% confidence interval [CI], 8.9–64.3mL/min) (P=.01). There was also a greater increase in lactate after FES-cycling (+1.5mmol/L [95% CI, .05–2.9mmol/L]; P=.01). FES-cycling did not change dyspnea or muscle fatigue compared with the placebo condition.
Conclusions
FES-cycling effectively increased exercise intensity in patients with COPD. Further studies should evaluate longer-term FES-cycling rehabilitation programs.
000003192 540__ $$acorrect
000003192 592__ $$aHESAV
000003192 592__ $$bUnité de recherche en santé, HESAV
000003192 592__ $$cSanté
000003192 592__ $$dPhysiothérapie
000003192 65017 $$aSanté
000003192 655__ $$ascientifique
000003192 6531_ $$9eng$$aexercise
000003192 6531_ $$9eng$$ametabolism
000003192 6531_ $$9eng$$apulmonary disease
000003192 6531_ $$9eng$$achronic obstructive
000003192 6531_ $$9eng$$arehabilitation
000003192 700__ $$aMedrinal, Clément$$uNormandy University, UNIROUEN, and the Institute for Research and Innovation in Biomedicine, Rouen, France ; Pulmonology Department, Le Havre Hospital, Montivilliers, France
000003192 700__ $$aPrieur, Guillaume$$uPulmonology Department, Le Havre Hospital, Montivilliers, France
000003192 700__ $$aCombret, Yann$$uInstitute for Experimental Research, Pulmonology, ORL & Dermatology, Catholic University of Louvain, Brussels, Belgium ; Physiotherapy Department, Le Havre Hospital, Montivilliers, France
000003192 700__ $$aRobledo Quesada, Aurora$$uIntensive Care Unit Department, Le Havre Hospital, Montivilliers, France
000003192 700__ $$aDebeaumont, David$$uExercise and Respiratory Physiology Department, Bois Guillaume Hospital, Rouen University Hospital, Rouen Cedex, France
000003192 700__ $$aBonnevie, Tristan$$uNormandy University, UNIROUEN, and the Institute for Research and Innovation in Biomedicine, Rouen, France ; ADIR Association, Bois Guillaume, France
000003192 700__ $$aGravier, Francis Edouard$$uNormandy University, UNIROUEN, and the Institute for Research and Innovation in Biomedicine, Rouen, France ; ADIR Association, Bois Guillaume, France
000003192 700__ $$aDupuis Lozeron, Elise$$uDivision of Clinical Epidemiology, Geneva University Hospitals, Geneva, Switzerland
000003192 700__ $$aQuieffin, Jean$$uPulmonology Department, Le Havre Hospital, Montivilliers, France
000003192 700__ $$aContal, Olivier$$uHESAV School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland
000003192 700__ $$aLamia, Bouchra$$uNormandy University, UNIROUEN, and the Institute for Research and Innovation in Biomedicine, Rouen, France ; Pulmonology Department, Le Havre Hospital, Montivilliers, France : Intensive Care Unit, Respiratory Department, Rouen University Hospital, Rouen, France
000003192 773__ $$g2018, vol. 99, no. 8, pp. 1454-1461$$tArchives of physical medicine and rehabilitation
000003192 85641 $$uhttps://doi.org/10.1016/j.apmr.2018.02.002$$zonline version
000003192 8564_ $$uhttps://hesso.tind.io/record/3192/files/Medrinal_2018_functional_ectrical_simulation.pdf$$s5152044
000003192 906__ $$aNONE
000003192 909CO $$pGLOBAL_SET$$ooai:hesso.tind.io:3192
000003192 950__ $$aSan2
000003192 981__ $$ascientifique
000003192 980__ $$ascientifique