Priorities for nutrition research in pediatric critical care

Tume, Lyvonne N. (University of the West of England, Bristol, UK) ; Valla, Frédéric V. (Hospices Civils de Lyon, Lyon-Bron, France ; The Hospital for Sick Children, Toronto, Canada) ; Floh, Alejandro A. (University of Toronto, Toronto, Canada) ; Goday, Praveen (Nutrition Medical College of Wisconsin, Milwaukee, Wisconsin, USA) ; Jotterand Chaparro, Corinne (Geneva School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland ; University Hospital of Lausanne, Lausanne, Switzerland) ; Larsen, Bodil (University of Alberta, Edmonton, Canada) ; Hau Lee, Jan (KK Women’s and Children’s Hospital, Singapore ; Duke-NUS Medical School, Singapore) ; Moreno, Yara M. F. (Santa Catarina Federal University, Santa Catarina, Brazil) ; Pathan, Nazima (University of Cambridge, Cambridge, England) ; Verbruggen, Sascha (Erasmus MC - Sophia Children’s Hospital, Rotterdam, the Netherlands) ; Mehta, Nilesh M. (Harvard Medical School, Boston, Massachusetts, USA)

Background : Widespread variation exists in pediatric critical care nutrition practices, largely because of the scarcity of evidence to guide best practice recommendations. Objective : The objective of this paper was to develop a list of topics to be prioritized for nutrition research in pediatric critical care in the next 10 years. Methods : A modified 3‐round Delphi process was undertaken by a newly established multidisciplinary group comprising 11 international researchers in the field of pediatric critical care nutrition. Items were ranked on a 5‐point Likert scale. Results : Forty‐five research topics (with a mean priority score >3(0‐5) were identified within the following 10 domains: the pathophysiology and impact of malnutrition in critical illness; nutrition assessment: nutrition risk assessment and biomarkers; accurate assessment of energy requirements in all phases of critical illness; the role of protein intake; the role of pharmaco‐nutrition; effective and safe delivery of enteral nutrition; enteral feeding intolerance: assessment and management; the role of parenteral nutrition; the impact of nutrition status and nutrition therapies on long‐term patient outcomes; and nutrition therapies for specific populations. Ten top research topics (that received a mean score >4(0‐5) were identified as the highest priority for research. Conclusions : This paper has identified important consensus‐derived priorities for clinical research in pediatric critical care nutrition. Future studies should determine topics that are a priority for patients and parents. Research funding should target these priority areas and promote an international collaborative approach to research in this field, with a focus on improving relevant patient outcomes.

Article Type:
HEdS - Genève
Aucun institut
10 p.
Published in:
Journal of parenteral and enteral nutrition
Numeration (vol. no.):
2019, vol. 43, no. 7, pp. 853-862
Appears in Collection:

 Record created 2020-02-11, last modified 2020-10-27

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