Development of a stand-alone integrated MEA biochip system for chronic recordings

De Pasquale, Paolo (School of Engineering, Architecture and Landscape (hepia), HES-SO // University of Applied Sciences Western Switzerland ; Istituto Italiano di Tecnologia (IIT), Genova, Italy) ; Sandoz, Antonin (School of Engineering, Architecture and Landscape (hepia), HES-SO // University of Applied Sciences Western Switzerland) ; Charvet, Igor (School of Engineering, Architecture and Landscape (hepia), HES-SO // University of Applied Sciences Western Switzerland) ; Passeraub, Philippe (School of Engineering, Architecture and Landscape (hepia), HES-SO // University of Applied Sciences Western Switzerland) ; Chiappalone, Michela (Istituto Italiano di Tecnologia (IIT), Genova, Italy) ; Stoppini, Luc (School of Engineering, Architecture and Landscape (hepia), HES-SO // University of Applied Sciences Western Switzerland)

Stand-alone integrated MEA system were developed and tested to investigate the effect of toxic compounds on network neural activities during chronic recordings. The system, consisting of specifically designed MEA aim to receive microfluidic organic substances and to communicate using wireless technology with the computer device. The system has been tested with several types of 2D and 3D neuronal cultures. The electrophysiological data are processed by NeuroSpy, a modify version of SpyCode. The software developed is able to analyze the basal activity, drug and stimulation evoked response.


Conference Type:
short paper
Faculty:
Ingénierie et Architecture
School:
HEPIA - Genève
Institute:
inSTI - Institut des Sciences et Technologies industrielles
Publisher:
Reutlingen, Germany, 1-7 July 2014
Date:
2014-07
Reutlingen, Germany
1-7 July 2014
Pagination:
2 p.
Published in:
Proceedings of 9th international meeting on substrate-integrated microelectrode arrays, 1-4 July 2014, Reutlingen, Germany
Appears in Collection:



 Record created 2020-03-06, last modified 2020-03-06

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