Blood cell dynamics in a simple model of microvascular networks

Clavica, Francesco (ARTORG Cardiovascular Engineering, University of Bern, Bern, Switzerland) ; Kämpfer-Homsy, Alexandra (School of Engineering – HE-Arc Ingénierie, HES-SO // University of Applied Sciences Western Switzerland) ; Jeandupeux, Laure (School of Engineering – HE-Arc Ingénierie, HES-SO // University of Applied Sciences Western Switzerland) ; Keppner, Herbert (School of Engineering – HE-Arc Ingénierie, HES-SO // University of Applied Sciences Western Switzerland) ; Obrist, Dominik (ARTORG Cardiovascular Engineering, University of Bern, Bern, Switzerland)

The dynamic distribution of red blood cells (RBCs) plays a crucial role in cerebral oxygenation, metabolism and many brain disorders (e.g. Alzheimer, ischemic stroke). Despite the growing number of studies on blood rheology in microcirculation, there remains still a big need for detailed experimental data on RBCs distribution in network of microchannels. To our best knowledge, this is the first experimental study of blood cell dynamics in simple networks of microchannels (height less than 10µm) under well controlled conditions which allows a systematic understanding of effects caused by single blood cells.


Keywords:
Conference Type:
short paper
Faculty:
Ingénierie et Architecture
School:
HE-Arc Ingénierie
Institute:
Aucun institut
Publisher:
Gyeongju, South Korea, 25-29 October 2015
Date:
2015-10
Gyeongju, South Korea
25-29 October 2015
Pagination:
3 p.
Published in:
Proceedings of 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 25-29 October 2015, Gyeongju, South Korea
Numeration (vol. no.):
pp. 1056-1058
ISBN:
978-0-9798064-8-3
Appears in Collection:



 Record created 2020-06-30, last modified 2020-07-14

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