SARS-CoV-2 vaccine willingness among pregnant and breastfeeding women during the first pandemic wave : a cross-sectional study in Switzerland

Stuckelberger, Sarah (Department Woman-Mother-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland) ; Favre, Guillaume (Department Woman-Mother-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland) ; Ceulemans, Michael (Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; Teratology Information Service, Pharmacovigilance Centre Lareb, Hertogenbosch, The Netherlands) ; Nordeng, Hedvig (Pharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, PharmaTox Strategic Initiative, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway; Department of Child Health and Development, Norwegian Institute of Public Health, Oslo, Norway) ; Gerbier, Eva (Department Woman-Mother-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland) ; Lambelet, Valentine (Department Woman-Mother-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland) ; Stojanov, Milos (Department Woman-Mother-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland) ; Winterfeld, Ursula (Swiss Teratogen Information Service, Service de Pharmacologie Clinique, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland) ; Baud, David (Department Woman-Mother-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland) ; Panchaud, Alice (Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland; Service of Pharmacy, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland) ; Pomar, Léo (Department Woman-Mother-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; HESAV School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland)

As pregnant women are at high risk of severe SARS-CoV-2 infection and COVID-19 vaccines are available in Switzerland, this study aimed to assess the willingness of Swiss pregnant and breastfeeding women to become vaccinated. Through a cross-sectional online study conducted after the first pandemic wave, vaccination practices and willingness to become vaccinated against SARS-CoV-2 if a vaccine was available were evaluated through binary, multi-choice, and open-ended questions. Factors associated with vaccine willingness were evaluated through univariable and multivariable analysis. A total of 1551 women responded to questions related to the primary outcome. Only 29.7% (153/515) of pregnant and 38.6% (400/1036) of breastfeeding women were willing to get vaccinated against SARS-CoV-2 if a vaccine had been available during the first wave. Positive predictors associated with SARS-CoV-2 vaccine acceptance were an age older than 40 years, a higher educational level, history of influenza vaccination within the previous year, having an obstetrician as the primary healthcare practitioner, and being in their third trimester of pregnancy. After the first pandemic wave, Switzerland had a low SARS-CoV-2 vaccination acceptance rate, emphasizing the need to identify and reduce barriers for immunization in pregnant and breastfeeding women, particularly among the youngest and those with a lower educational level.


Keywords:
Article Type:
scientifique
Faculty:
Santé
Branch:
Sage-femme
School:
HESAV
Institute:
Unité de recherche en santé, HESAV
Date:
2021-07
Pagination:
13 p.
Published in:
Viruses
Numeration (vol. no.):
July 2021, vol. 13, no. 7, Article 1199
DOI:
ISSN:
1999-4915
Appears in Collection:



 Record created 2021-07-09, last modified 2021-07-09

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